Luton defeated Reading in an all-championship second round tie of the Carabao cup as they set up a clash against Manchester United.
United will have to travel to Luton as they will play in the competition for the first time.
The Hatters began impressively and went ahead in the 24th minute when Jordan Clark guided in a clever far-post header.
Manchester United were knocked out in the semifinal of the competition by Chelsea last season.
And will seek to past that mark when they begin their journey against the Championship side.